SCHEMBL31467993

SCHEMBL31467993

CC(C)C(C(N)=O)N(C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.44
SLC6A4 P31645 3/20 0.44
ALOX5 P09917 1/20 0.41
MMP2 P08253 2/20 0.40
MMP9 P14780 2/20 0.40
MMP8 P22894 2/20 0.40
MMP13 P45452 2/20 0.40
ADAMTS4 O75173 1/20 0.40
PLAU P00749 1/20 0.39
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.37
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3340749 0.85 ADAMTS4 (0.49) SLC6A2SLC6A4MMP2MMP9MMP8
SCHEMBL3340746 0.85 ADAMTS4 (0.49) SLC6A2SLC6A4MMP2MMP9MMP8
SCHEMBL31467998 0.84 ALOX5 (0.42) SLC6A2SLC6A4ALOX5ALDH1A1LMNA
SCHEMBL31467994 0.82 CHRM5 (0.41) SLC6A2LMNASMN1; SMN2HTTKMT2A
SCHEMBL31467995 0.82 SIGMAR1 (0.43) SLC6A2SLC6A4ALDH1A1LMNATP53
SCHEMBL1821413 0.81 ALOX5 (0.43) SLC6A2SLC6A4ALOX5ALDH1A1LMNA
SCHEMBL8586520 0.81 ALOX5 (0.43) SLC6A2SLC6A4ALOX5ALDH1A1LMNA
SCHEMBL31468000 0.80 F7 (0.41) MMP2MMP9MMP8MMP13ADAMTS4
Carbamic Acid SCHEMBL27977071 0.79 ALDH1A1 (0.46) SLC6A2SLC6A4ALOX5ALDH1A1LMNA
SCHEMBL26324873 0.77 TSHR (0.41) SLC6A2SLC6A4MMP2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025045233-A1 MACROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF 劲方医药科技(上海)股份有限公司 2025-03-06 WO disclosed