Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5890020 | 0.88 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ARAB9ATSHR | |
| SCHEMBL6828614 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TDP1HPGDTRIM24ALDH5A1 | |
| SCHEMBL27826474 | 0.81 | BACE1 (0.38) | ALDH1A1LMNABACE1 | |
| SCHEMBL4963369 | 0.81 | CYP19A1 (0.40) | ALDH1A1TSHRGAAMAPK1KDM4E | |
| SCHEMBL6535578 | 0.80 | ESR1 (0.55) | TDP1TP53VDRAR | |
| SCHEMBL3436061 | 0.80 | MAOB (0.50) | MAOBMEN1KMT2ASLC22A6SLC22A8 | |
| SCHEMBL27800149 | 0.79 | TSHR (0.53) | ALDH1A1TDP1MAOBMEN1KMT2A | |
| SCHEMBL12345248 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1HPGDTRIM24ALDH5A1 | |
| SCHEMBL20942165 | 0.78 | CNR2 (0.52) | MAOBTSHRGAAMAPK1KDM4E | |
| SCHEMBL22566844 | 0.76 | MAOB (0.55) | MAOBTSHRMAPK1ABCB1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040230073-A1 | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | AJINOMOTO CO., INC. (JP) | 2004-11-18 | — | — | US | disclosed |
| US-20020132032-A1 | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | AJINOMOTO CO., INC. (JP) | 2002-09-19 | — | — | US | disclosed |
| EP-1219633-A1 | PROCESS FOR PRODUCING ASPARTAME DERIVATIVE, CRYSTALS THEREOF, NOVEL PRODUCTION INTERMEDIATES THEREFOR AND PROCESS FOR PRODUCING THE INTERMEDIATE | Ajinomoto Co., Inc. (JP) | 2002-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040230073-A1 | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | IAPP, DPP4, SI | ALDH1A1 1421/4885TDP1 3199/4885HPGD 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.