Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828554 | 0.84 | CNR1 (0.39) | CYP19A1TSHRMAPK1GAAVDR | |
| SCHEMBL5890020 | 0.84 | ALDH1A1 (0.50) | TSHRGAAALDH1A1CNR1CNR2 | |
| SCHEMBL27826474 | 0.81 | BACE1 (0.38) | ALDH1A1 | |
| SCHEMBL6828613 | 0.81 | ALDH1A1 (0.50) | TSHRMAPK1GAAVDRALDH1A1 | |
| SCHEMBL8579692 | 0.79 | VDR (0.44) | CYP19A1MAPK1GAAVDRALDH1A1 | |
| SCHEMBL4963469 | 0.78 | MRGPRX4 (0.52) | TSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL253549 | 0.77 | CYP19A1 (0.43) | CYP19A1TSHRMAPK1GAAVDR | |
| SCHEMBL4960983 | 0.76 | SMPD1 (0.49) | MAPK1ALDH1A1KDM4E | |
| SCHEMBL4963434 | 0.76 | HPGD (0.50) | ALDH1A1KDM4E | |
| SCHEMBL6535578 | 0.76 | ESR1 (0.55) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689902-B2 | REDUCTIVE ALKYLATION | AJINOMOTO CO., INC. (JP) | 2004-02-10 | — | — | US | claimed |
| US-20030032842-A1 | Novel arylpropyl aldehyde derivatives, processes for producing the same, and methods of using the same | AJINOMOTO CO., INC. (JP) | 2003-02-13 | — | — | US | claimed |
| EP-1249442-A1 | NOVEL ARYLPROPIONALDEHYDE DERIVATIVES AND PRODUCTION AND USE OF THE SAME | Ajinomoto Co., Inc. (JP) | 2002-10-16 | — | — | EP | claimed |
| EP-1114828-B1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | AJINOMOTO KK (JP) | 2008-03-12 | — | — | EP | disclosed |
| US-7238830-B2 | N-alkylaspartyl dipeptide ester compounds | AJINOMOTO CO., INC. (JP) | 2007-07-03 | — | — | US | disclosed |
| CN-1206238-C | N-alkylaspartyldipeptide ester derivatives and sweeteners | AJINOMOTO KK (JP) | 2005-06-15 | — | — | CN | disclosed |
| US-20040230073-A1 | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | AJINOMOTO CO., INC. (JP) | 2004-11-18 | — | — | US | disclosed |
| US-6689902-B2 | REDUCTIVE ALKYLATION | AJINOMOTO CO., INC. (JP) | 2004-02-10 | — | — | US | disclosed |
| US-20030032842-A1 | Novel arylpropyl aldehyde derivatives, processes for producing the same, and methods of using the same | AJINOMOTO CO., INC. (JP) | 2003-02-13 | — | — | US | disclosed |
| EP-1249442-A1 | NOVEL ARYLPROPIONALDEHYDE DERIVATIVES AND PRODUCTION AND USE OF THE SAME | Ajinomoto Co., Inc. (JP) | 2002-10-16 | — | — | EP | disclosed |
| US-20020132032-A1 | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | AJINOMOTO CO., INC. (JP) | 2002-09-19 | — | — | US | disclosed |
| EP-1219633-A1 | PROCESS FOR PRODUCING ASPARTAME DERIVATIVE, CRYSTALS THEREOF, NOVEL PRODUCTION INTERMEDIATES THEREFOR AND PROCESS FOR PRODUCING THE INTERMEDIATE | Ajinomoto Co., Inc. (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-20010039357-A1 | N-alkylaspartyl dipeptide ester compounds | AJINOMOTO CO., INC. (JP) | 2001-11-08 | — | — | US | disclosed |
| CN-1315959-A | N-Alkylaspartyldipeptide ester derivatives and sweeteners | AJINOMOTO KK (JP) | 2001-10-03 | — | — | CN | disclosed |
| EP-1114828-A1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | Ajinomoto Co., Inc. (JP) | 2001-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039357-A1 | N-alkylaspartyl dipeptide ester compounds | DNPEP, ANPEP, ASNS | CYP19A1 4812/4885TSHR 4681/4885MAPK1 2954/4885 |
| US-20030032842-A1 | Novel arylpropyl aldehyde derivatives, processes for producing the same, and methods of using the same | ALDH7A1, ASPH, DDC | CYP19A1 3613/4885TSHR 4286/4885MAPK1 3290/4885 |
| US-20040230073-A1 | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | IAPP, DPP4, SI | CYP19A1 2680/4885TSHR 4663/4885MAPK1 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.