Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829309 | 0.84 | KMT2A (0.49) | PRSS1TMPRSS15KMT2AGLATSHR | |
| SCHEMBL6828651 | 0.81 | PRSS1 (0.45) | PRSS1TMPRSS15KMT2AGLATSHR | |
| SCHEMBL6826474 | 0.80 | ALDH1A1 (0.41) | PRSS1TMPRSS15KMT2AGLATSHR | |
| SCHEMBL6829604 | 0.79 | PRSS1 (0.48) | PRSS1TMPRSS15KMT2AGLATSHR | |
| SCHEMBL6831061 | 0.78 | MAPT (0.51) | PRSS1TMPRSS15KMT2AGLATSHR | |
| SCHEMBL6826476 | 0.78 | KMT2A (0.63) | PRSS1TMPRSS15KMT2AGLATSHR | |
| SCHEMBL6829246 | 0.78 | KMT2A (0.51) | PRSS1TMPRSS15KMT2AGLATSHR | |
| SCHEMBL6831027 | 0.77 | LMNA (0.51) | PRSS1TMPRSS15KMT2AALDH1A1KDM4E | |
| SCHEMBL6828650 | 0.77 | KDM4E (0.43) | PRSS1TMPRSS15KMT2ATSHRALDH1A1 | |
| SCHEMBL6828603 | 0.77 | KIF11 (0.44) | PRSS1TMPRSS15KMT2AGLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |