Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828651 | 0.84 | PRSS1 (0.45) | ALDH1A1LMNAPRSS1TMPRSS15SMN1; SMN2 | |
| SCHEMBL6828819 | 0.80 | PRSS1 (0.40) | ALDH1A1POLBLMNAPRSS1TMPRSS15 | |
| SCHEMBL6829604 | 0.79 | PRSS1 (0.48) | ALDH1A1POLBLMNAPRSS1TMPRSS15 | |
| SCHEMBL6829332 | 0.78 | ALDH1A1 (0.39) | ALDH1A1POLBLMNAPRSS1TMPRSS15 | |
| SCHEMBL6921975 | 0.78 | RAB9A (0.38) | ALDH1A1POLBLMNASMN1; SMN2KMT2A | |
| SCHEMBL6829246 | 0.78 | KMT2A (0.51) | ALDH1A1LMNAPRSS1TMPRSS15SMN1; SMN2 | |
| SCHEMBL6831061 | 0.78 | MAPT (0.51) | ALDH1A1LMNAPRSS1TMPRSS15SMN1; SMN2 | |
| SCHEMBL6829309 | 0.78 | KMT2A (0.49) | ALDH1A1POLBLMNAPRSS1TMPRSS15 | |
| SCHEMBL6826476 | 0.78 | KMT2A (0.63) | ALDH1A1POLBLMNAPRSS1TMPRSS15 | |
| SCHEMBL6831027 | 0.77 | LMNA (0.51) | ALDH1A1POLBLMNAPRSS1TMPRSS15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |