Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MGAM | O43451 | 3/20 | 0.39 |
| ▸ | SI | P14410 | 3/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828953 | 0.79 | TERT (0.51) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL6829200 | 0.75 | TERT (0.54) | ALDH1A1KDM4ELMNAGAAMGAM | |
| SCHEMBL6828650 | 0.74 | KDM4E (0.43) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL6826082 | 0.74 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNAGAAMGAM | |
| SCHEMBL6828867 | 0.71 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL6826092 | 0.71 | TERT (0.55) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL6831128 | 0.71 | TERT (0.55) | ALDH1A1KDM4ELMNAGAAMGAM | |
| SCHEMBL6829795 | 0.71 | TERT (0.53) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL6831134 | 0.71 | RAB9A (0.40) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL6826130 | 0.70 | KMT2A (0.41) | ALDH1A1KDM4EGAAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |