Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831134 | 0.82 | RAB9A (0.40) | ALDH1A1HPGDLMNATP53MAPT | |
| SCHEMBL6830047 | 0.79 | MAPT (0.41) | ALDH1A1HPGDKMT2ALMNAMAPT | |
| SCHEMBL6829660 | 0.77 | TERT (0.58) | ALDH1A1HPGDKMT2ATP53MAPT | |
| SCHEMBL6829620 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL6829197 | 0.73 | POLB (0.55) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL6828837 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL6828989 | 0.71 | ALDH1A1 (0.42) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL6826092 | 0.71 | TERT (0.55) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL6826489 | 0.71 | TERT (0.68) | ALDH1A1MEN1KMT2AL3MBTL1TERT | |
| SCHEMBL6831128 | 0.71 | TERT (0.55) | ALDH1A1MEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |