Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7131180 | 0.86 | MAOB (0.51) | MAOBRAB9ATDP1NPC1KMT2A | |
| SCHEMBL6829308 | 0.79 | MRGPRX4 (0.47) | RAB9ANPC1MRGPRX4 | |
| SCHEMBL6920177 | 0.75 | NPC1 (0.40) | MAOBRAB9ATDP1NPC1 | |
| SCHEMBL7134471 | 0.75 | DAO (0.43) | MAOBRAB9ATDP1NPC1LMNA | |
| SCHEMBL7128455 | 0.75 | MRGPRX4 (0.55) | MAOBRAB9ANPC1APPLMNA | |
| SCHEMBL9900205 | 0.74 | ADRA1D (0.43) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL7126366 | 0.73 | L3MBTL1 (0.43) | MAOBRAB9ANPC1APPKMT2A | |
| SCHEMBL6828965 | 0.73 | MAOB (0.40) | MAOBRAB9ATDP1NPC1APP | |
| SCHEMBL12177801 | 0.72 | HDAC6 (0.55) | APPALDH1A1 | |
| SCHEMBL6923233 | 0.71 | ADRA1D (0.45) | RAB9ATDP1NPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |