Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126366 | 0.84 | L3MBTL1 (0.43) | MAOBMAOAAPPCA12CA1 | |
| SCHEMBL6829285 | 0.80 | MAOB (0.44) | MAOBMRGPRX4ALDH1A1LMNAKMT2A | |
| SCHEMBL6920177 | 0.77 | NPC1 (0.40) | MAOBMAOATDP1NPC1RAB9A | |
| SCHEMBL7134471 | 0.77 | DAO (0.43) | MAOBMAOAMRGPRX4ALDH1A1LMNA | |
| SCHEMBL7131180 | 0.73 | MAOB (0.51) | MAOBMAOAFFAR1ALDH1A1KMT2A | |
| SCHEMBL6828913 | 0.73 | MAOB (0.49) | MAOBAPPMRGPRX4ALDH1A1LMNA | |
| SCHEMBL7130916 | 0.72 | MAPT (0.39) | ALDH1A1TDP1 | |
| SCHEMBL9900205 | 0.72 | ADRA1D (0.43) | ALDH1A1KMT2ACYP2C9CYP2C19KDM4E | |
| SCHEMBL6829566 | 0.70 | MRGPRX4 (0.54) | MAOBRXRARXRBFFAR1FFAR4 | |
| SCHEMBL16901841 | 0.69 | DPP4 (0.45) | APPALDH1A1KMT2ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |