Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831060 | 0.83 | THRB (0.49) | THRBMAPK1LMNAKMT2APOLB | |
| SCHEMBL6919997 | 0.82 | CYP1A2 (0.48) | LMNAKMT2AALDH1A1 | |
| SCHEMBL28588234 | 0.76 | RAB9A (0.50) | MAPK1LMNAALDH1A1 | |
| SCHEMBL30180494 | 0.76 | RAB9A (0.50) | MAPK1LMNAALDH1A1 | |
| SCHEMBL6644390 | 0.73 | IDO1 (0.47) | THRBIDO1LMNAKMT2APOLB | |
| SCHEMBL6829032 | 0.72 | KMT2A (0.40) | THRBIDO1LMNAKMT2AALDH1A1 | |
| SCHEMBL6927192 | 0.69 | THRB (0.39) | THRBIDO1LMNA | |
| SCHEMBL13403361 | 0.69 | PTGS1 (0.51) | PTGS1KMT2A | |
| SCHEMBL29317589 | 0.69 | DEGS1 (0.52) | THRBKMT2APOLB | |
| SCHEMBL3861581 | 0.69 | LTA4H (0.45) | THRBIDO1PTGS1LMNAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |