Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11724286 | 0.76 | TSHR (0.39) | HTTKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL1636797 | 0.76 | TSHR (0.48) | HTTKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL28215177 | 0.75 | HTT (0.52) | HTTKMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL1531216 | 0.73 | CYP19A1 (0.38) | HTTKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL11730933 | 0.72 | LMNA (0.39) | HTTKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL896533 | 0.72 | ALDH1A1 (0.42) | HTTKMT2ATSHRALDH1A1CYP19A1 | |
| SCHEMBL1036242 | 0.72 | ALDH1A1 (0.37) | HTTKMT2ASMN1; SMN2MEN1TSHR | |
| SCHEMBL10967569 | 0.69 | HTT (0.46) | HTTKMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL6829475 | 0.69 | TSHR (0.42) | HTTKMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL1034794 | 0.68 | PTGS2 (0.39) | HTTKMT2AL3MBTL1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |