Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218286 | 0.90 | ADORA2A (0.44) | AHCYADORA2AADORA2BCDK1CCNB1 | |
| SCHEMBL29721329 | 0.86 | ADORA3 (0.50) | AHCYADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL7435441 | 0.86 | ADORA3 (0.50) | AHCYADORA2AADORA2BADORA3ADORA1 | |
| Benzene SCHEMBL27650186 | 0.84 | PI4KA (0.48) | AHCYADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6685951 | 0.83 | AHCY (0.46) | AHCYADORA2AADORA2BCDK1CCNB1 | |
| SCHEMBL1938201 | 0.83 | AHCY (0.46) | AHCYADORA2AADORA2BCDK1CCNB1 | |
| SCHEMBL6393079 | 0.81 | BLM (0.45) | ADORA3 | |
| SCHEMBL2270700 | 0.78 | ADORA2A (0.51) | AHCYADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL31170697 | 0.78 | PI4KA (0.39) | ADORA1 | |
| SCHEMBL27597373 | 0.78 | PI4KA (0.39) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214198-A1 | Allele-targeted RNA interference | UNIVERSITY OF MASSACHUSETTS | 2004-10-28 | — | — | US | disclosed |
| WO-2004046324-A2 | ALLELE-TARGETED RNA INTERFERENCE | UNIVERSITY OF MASSACHUSETTS (US) | 2004-06-03 | — | — | WO | disclosed |