Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829943 | 0.88 | HTR6 (0.46) | AVPR1BHTR6ALDH1A1HPGDCYP3A4 | |
| SCHEMBL6826756 | 0.86 | DRD2 (0.54) | DRD2DRD3HTR6ALDH1A1HPGD | |
| SCHEMBL6831430 | 0.81 | SLC2A1 (0.55) | DRD2DRD3HTR6ALDH1A1HPGD | |
| SCHEMBL6830157 | 0.79 | HTR6 (0.59) | HTR6CYP3A4CYP2C19ADRA2ACYP2D6 | |
| SCHEMBL6829317 | 0.79 | HTR6 (0.49) | HTR6ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL6829881 | 0.79 | SLC2A1 (0.56) | HTR6ALDH1A1HPGDHRH4TSHR | |
| SCHEMBL6830116 | 0.79 | KDM4E (0.51) | HTR6ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL946638 | 0.78 | HTR6 (0.55) | HTR6ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL6829294 | 0.76 | HTR6 (0.50) | HTR6KMT2AMEN1CYP3A4CYP2C19 | |
| SCHEMBL6826373 | 0.75 | HRH3 (0.58) | HTR6ALDH1A1HPGDKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | claimed |
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |