Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829943 | 0.87 | HTR6 (0.46) | HTR6SLC2A1ACLYCYP3A4CYP2D6 | |
| SCHEMBL6826389 | 0.84 | LMNA (0.47) | HTR6SLC2A1ACLYHRH4 | |
| SCHEMBL6826365 | 0.77 | SLC2A1 (0.57) | HTR6SLC2A1ACLYMEN1KMT2A | |
| SCHEMBL6829313 | 0.76 | DRD2 (0.48) | HTR6ACLYCYP3A4ADRA2ACYP2D6 | |
| SCHEMBL6826421 | 0.72 | SLC2A1 (0.55) | SLC2A1KMT2A | |
| SCHEMBL6829881 | 0.71 | SLC2A1 (0.56) | HTR6SLC2A1HRH4 | |
| SCHEMBL6826439 | 0.71 | LMNA (0.50) | SLC2A1ACLYCYP2C19HRH4 | |
| SCHEMBL6826410 | 0.70 | SLC2A1 (0.55) | HTR6SLC2A1ACLYCHRM1CYP3A4 | |
| SCHEMBL6831430 | 0.70 | SLC2A1 (0.55) | HTR6SLC2A1HRH4MEN1KMT2A | |
| SCHEMBL6826574 | 0.69 | HTR6 (0.53) | HTR6CYP3A4CYP2D6HRH4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | claimed |
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |