Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829313 | 0.88 | DRD2 (0.48) | HTR6HRH4ACLYALOX5HPGD | |
| SCHEMBL6829294 | 0.87 | HTR6 (0.50) | HTR6HRH4ACLYSLC2A1CYP3A4 | |
| SCHEMBL6829881 | 0.84 | SLC2A1 (0.56) | HTR6HRH4ALOX5HPGDTSHR | |
| SCHEMBL6829301 | 0.80 | NOD2 (0.60) | HTR6ALOX5SLC2A1CYP3A4CYP2D6 | |
| SCHEMBL6924887 | 0.78 | ALOX5 (0.52) | HTR6ALOX5HPGDTSHRSLC2A1 | |
| SCHEMBL6826756 | 0.78 | DRD2 (0.54) | HTR6ALOX5HPGDTSHRSLC2A1 | |
| SCHEMBL6826574 | 0.77 | HTR6 (0.53) | HTR6HRH4AVPR1BCYP3A4CYP2D6 | |
| SCHEMBL6829699 | 0.76 | HTR6 (0.60) | HTR6CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5029975 | 0.75 | CCR2 (0.44) | ACLYALOX5TSHRALDH1A1 | |
| SCHEMBL6141961 | 0.75 | DRD2 (0.60) | HRH4HPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | claimed |
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |