Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826496 | 0.90 | SLC2A1 (0.54) | HRH3SLC2A1HTR6LMNAGAA | |
| SCHEMBL6924163 | 0.89 | SLC2A1 (0.43) | HRH3SLC2A1GPR183HTR6LMNA | |
| SCHEMBL6921864 | 0.86 | HRH3 (0.51) | HRH3SLC2A1NOD2NOD1GPR183 | |
| SCHEMBL6829301 | 0.83 | NOD2 (0.60) | HRH3SLC2A1NOD2NOD1HTR6 | |
| SCHEMBL6826779 | 0.83 | HTR6 (0.44) | SLC2A1HTR6LMNAGAA | |
| SCHEMBL6829377 | 0.83 | HRH3 (0.53) | HRH3SLC2A1NOD2NOD1GPR183 | |
| SCHEMBL6826373 | 0.83 | HRH3 (0.58) | HRH3SLC2A1NOD2NOD1GPR183 | |
| SCHEMBL6829140 | 0.81 | HRH3 (0.55) | HRH3SLC2A1NOD2NOD1LMNA | |
| SCHEMBL6925689 | 0.76 | SLC2A1 (0.48) | HRH3SLC2A1HTR6LMNAGAA | |
| SCHEMBL6830116 | 0.76 | KDM4E (0.51) | HRH3SLC2A1HTR6LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | claimed |
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |