Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.60 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829881 | 0.91 | SLC2A1 (0.56) | NOD2NOD1ALOX5SLC2A1HTR6 | |
| SCHEMBL6826756 | 0.87 | DRD2 (0.54) | NOD2NOD1ALOX5SLC2A1HTR6 | |
| SCHEMBL6921864 | 0.87 | HRH3 (0.51) | NOD2NOD1ALOX5HRH3SLC2A1 | |
| SCHEMBL6924887 | 0.87 | ALOX5 (0.52) | NOD2NOD1ALOX5SLC2A1HTR6 | |
| SCHEMBL6826373 | 0.84 | HRH3 (0.58) | NOD2NOD1HRH3SLC2A1HTR6 | |
| SCHEMBL6829377 | 0.84 | HRH3 (0.53) | NOD2NOD1HRH3SLC2A1HTR6 | |
| SCHEMBL6829439 | 0.83 | HRH3 (0.49) | NOD2NOD1ALOX5HRH3SLC2A1 | |
| SCHEMBL6829140 | 0.82 | HRH3 (0.55) | NOD2NOD1HRH3SLC2A1CYP3A4 | |
| SCHEMBL6829943 | 0.80 | HTR6 (0.46) | ALOX5SLC2A1HTR6CYP3A4CYP2D6 | |
| SCHEMBL10259849 | 0.78 | GAA (0.59) | ALOX5SLC2A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | claimed |
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |