Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 10/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829429 | 0.94 | RBP4 (0.41) | RBP4MAPTMAPK1TDP1ALDH1A1 | |
| SCHEMBL8305045 | 0.81 | RBP4 (0.50) | RBP4MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL28092503 | 0.80 | TDP1 (0.46) | MAPTMAPK1TDP1ALDH1A1MEN1 | |
| SCHEMBL6786475 | 0.76 | MEN1 (0.66) | RBP4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6791221 | 0.76 | MAPK1 (0.47) | RBP4MAPTMAPK1TDP1ALDH1A1 | |
| SCHEMBL2205192 | 0.74 | HTR2C (0.50) | MAPTMAPK1TDP1ALDH1A1 | |
| Nitric Acid SCHEMBL6720251 | 0.74 | MAPK1 (0.46) | RBP4MAPTMAPK1TDP1ALDH1A1 | |
| SCHEMBL6827413 | 0.74 | MAPT (0.42) | MAPTMAPK1TDP1ALDH1A1KMT2A | |
| SCHEMBL9671327 | 0.72 | HPGDS (0.44) | RBP4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6827610 | 0.71 | MEN1 (0.59) | RBP4MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004010943-A2 | SUBSTITUTED BENZANILIDES AS MODULATORS OF THE CCR5 RECEPTOR | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |