Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 5/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829470 | 0.94 | RBP4 (0.44) | RBP4MAPTMAPK1TDP1KMT2A | |
| SCHEMBL9671327 | 0.80 | HPGDS (0.44) | RBP4PIK3CDMAPTKMT2AMEN1 | |
| SCHEMBL2274616 | 0.77 | MEN1 (0.60) | RBP4MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6827316 | 0.77 | MAPK1 (0.44) | MAPTMAPK1KMT2AALDH1A1 | |
| SCHEMBL6827413 | 0.77 | MAPT (0.42) | MAPTMAPK1TDP1KDM4EKMT2A | |
| SCHEMBL28092503 | 0.76 | TDP1 (0.46) | MAPTMAPK1TDP1KDM4EKMT2A | |
| SCHEMBL8305045 | 0.75 | RBP4 (0.50) | RBP4KMT2AMEN1 | |
| SCHEMBL10491630 | 0.73 | ALDH1A1 (0.41) | PIK3CDMAPTKMT2AALDH1A1 | |
| SCHEMBL10491617 | 0.73 | ALDH1A1 (0.41) | PIK3CDMAPTKMT2AALDH1A1 | |
| SCHEMBL9827862 | 0.72 | ALDH1A1 (0.49) | PIK3CDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004010943-A2 | SUBSTITUTED BENZANILIDES AS MODULATORS OF THE CCR5 RECEPTOR | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |