Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 17/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829470 | 0.81 | RBP4 (0.44) | RBP4MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL6786475 | 0.80 | MEN1 (0.66) | RBP4MEN1KMT2A | |
| SCHEMBL521037 | 0.77 | HTR1D (0.43) | MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL28092534 | 0.77 | HTR2C (0.43) | — | |
| SCHEMBL6815771 | 0.76 | MEN1 (0.45) | RBP4MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL6829429 | 0.75 | RBP4 (0.41) | RBP4MEN1KMT2A | |
| SCHEMBL6827614 | 0.75 | MEN1 (0.59) | RBP4MEN1KMT2A | |
| SCHEMBL6827610 | 0.75 | MEN1 (0.59) | RBP4MEN1KMT2A | |
| SCHEMBL7065427 | 0.74 | PARP1 (0.39) | MEN1KMT2AKCNH2 | |
| SCHEMBL20516110 | 0.73 | QDPR (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |