Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GLP1R | P43220 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591928 | 0.78 | BACE1 (0.61) | KMT2ALMNAGLACYP2C9BACE1 | |
| SCHEMBL4275648 | 0.72 | NISCH (0.41) | LMNAGLACYP2C9HPGDALDH1A1 | |
| SCHEMBL6589904 | 0.71 | BACE1 (0.53) | KMT2ALMNAGLACYP2C9BACE1 | |
| SCHEMBL6591279 | 0.71 | BACE1 (0.53) | KMT2ALMNAGLACYP2C9BACE1 | |
| SCHEMBL6589473 | 0.71 | BACE1 (0.53) | KMT2ALMNAGLACYP2C9BACE1 | |
| SCHEMBL6590512 | 0.71 | BACE1 (0.49) | KMT2ALMNAGLACYP2C9BACE1 | |
| SCHEMBL6587050 | 0.70 | LMNA (0.51) | KMT2ALMNAGLACYP2C9BACE1 | |
| SCHEMBL6587747 | 0.69 | BACE1 (0.43) | KMT2ALMNAGLACYP2C9BACE1 | |
| SCHEMBL6588437 | 0.69 | BACE1 (0.50) | KMT2ALMNAGLACYP2C9BACE1 | |
| SCHEMBL6600448 | 0.68 | BACE1 (0.49) | KMT2ALMNAGLACYP2C9BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058727-A1 | SUBSTITUTED 3,5-DIHYDRO-4H-IMIDAZOL-4-ONES FOR THE TREATMENT OF OBESITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |