Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CD38 | P28907 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126167 | 0.85 | RAB9A (0.54) | TERTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6831025 | 0.81 | RAB9A (0.60) | TERTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6925421 | 0.81 | GRM4 (0.59) | TERTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL13550114 | 0.80 | KMT2A (0.62) | MEN1KMT2ARXFP1RAB9ANPSR1 | |
| SCHEMBL6829663 | 0.78 | TERT (0.59) | TERTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6831237 | 0.77 | TERT (0.58) | TERTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6831113 | 0.77 | MAPT (0.62) | TERTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL30643208 | 0.77 | KDR (0.72) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29723905 | 0.77 | KDR (0.72) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL259238 | 0.77 | KDR (0.72) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008091681-A2 | THERAMUTEIN MODULATORS | HOUSEY GERARD M (US) | 2008-07-31 | — | — | WO | disclosed |
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |