Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130324 | 0.99 | ESR1 (0.38) | ESR1HTTTSHRLMNAPOLB | |
| SCHEMBL6130322 | 0.88 | ESR1 (0.39) | ESR1HTTTSHRLMNAPOLB | |
| SCHEMBL11823240 | 0.79 | HTR1A (0.40) | AOC3SMN1; SMN2 | |
| SCHEMBL6253134 | 0.77 | PER2 (0.41) | ESR1HTTTSHRLMNAHPGD | |
| SCHEMBL8650210 | 0.74 | LMNA (0.44) | ESR1HTTLMNAPOLBHPGD | |
| SCHEMBL242597 | 0.74 | ESR1 (0.47) | ESR1HTTLMNAKMT2AAOC3 | |
| SCHEMBL6480203 | 0.73 | LMNA (0.46) | ESR1HTTLMNAPOLBHPGD | |
| SCHEMBL27434036 | 0.73 | LMNA (0.39) | LMNAPOLBMAPTALDH1A1KDM4E | |
| SCHEMBL9879559 | 0.73 | ESR1 (0.46) | ESR1HTTLMNAKMT2AAOC3 | |
| SCHEMBL17685583 | 0.73 | ESR1 (0.49) | ESR1HTTLMNAKMT2AAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |