Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480203 | 0.99 | LMNA (0.46) | LMNAHPGDPOLBGAAHTT | |
| SCHEMBL6480197 | 0.87 | LMNA (0.42) | LMNAHPGDPOLBGAAHTT | |
| SCHEMBL6829518 | 0.74 | ESR1 (0.38) | LMNAHPGDPOLBGAAHTT | |
| SCHEMBL6130324 | 0.74 | ESR1 (0.38) | LMNAHPGDPOLBGAAHTT | |
| SCHEMBL2214193 | 0.70 | CA1 (0.48) | LMNAHTTESR1SLC6A2SLC6A4 | |
| SCHEMBL3794136 | 0.70 | PER2 (0.44) | LMNAHPGDGAAHTTESR1 | |
| Potassium SCHEMBL5140869 | 0.69 | PER2 (0.43) | LMNAHPGDGAAHTTESR1 | |
| SCHEMBL9822605 | 0.68 | ESR1 (0.47) | LMNAHPGDPOLBESR1PAX8 | |
| SCHEMBL6129999 | 0.68 | APEX1 (0.34) | LMNAHPGDHTTKMT2AMEN1 | |
| SCHEMBL6253134 | 0.67 | PER2 (0.41) | LMNAHPGDHTTESR1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5790627-A | Method and apparatus for observing a specimen using an X-ray microscope | RESEARCH DEVELOPMENT CORP. (JP) | 1998-08-04 | — | — | US | disclosed |