SCHEMBL6829666

SCHEMBL6829666

CCc1cccc([O])c1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.46
GABRB2 P47870 4/20 0.46
HTR1A P08908 3/20 0.46
DRD2 P14416 3/20 0.46
DRD4 P21917 3/20 0.46
HTR2A P28223 3/20 0.46
HTR2C P28335 3/20 0.46
DRD3 P35462 3/20 0.46
PNMT P11086 1/20 0.38
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CTRC Q99895 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
GPR35 Q9HC97 1/20 0.34
IDO1 P14902 1/20 0.33
MGLL Q99685 1/20 0.33
PDK2 Q15119 1/20 0.33
CSNK2A2 P19784 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2200675 0.85 GABRA1 (0.55) GABRA1GABRB2HTR1ADRD2DRD4
Nitrogen SCHEMBL10979594 0.80 GABRA1 (0.50) GABRA1GABRB2HTR1ADRD2DRD4
SCHEMBL91279 0.78 PNMT (0.62) GABRA1GABRB2HTR1ADRD2DRD4
SCHEMBL6712668 0.77 HTR1A (0.43) GABRA1GABRB2HTR1ADRD2DRD4
SCHEMBL3781759 0.76 GABRA1 (0.46) GABRA1GABRB2HTR1ADRD2DRD4
SCHEMBL7788783 0.76 GABRA1 (0.48) GABRA1GABRB2HTR1ADRD2DRD4
SCHEMBL15788838 0.76 HTR2C (0.42) GABRA1GABRB2HTR1ADRD2DRD4
SCHEMBL17450488 0.74 GABRA1 (0.44) GABRA1GABRB2HTR1ADRD2DRD4
SCHEMBL16959855 0.74 GABRA1 (0.45) GABRA1GABRB2HTR1ADRD2DRD4
SCHEMBL16950743 0.74 GABRA1 (0.50) GABRA1GABRB2HTR1ADRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6746757-B1 Multilayered molding MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-06-08 US disclosed
EP-0852604-B1 A POLYPHENYLENE OXIDE DELIVERY SYSTEM FOR ADHESIVE COMPOSITIONS ARIZONA CHEM (US) 2002-04-10 EP disclosed
US-5910526-A HEATING AND MIXING PREBLEND COMPRISING A POLYPHENYLENE ETHER AND B-BLOCK COMPATIBLE RESIN TOGETHER WITH STYRENIC-CONJUGATED DIENE-STRYRENIC-A-B-A BLOCK POLYMER; HIGHER TEMPERAURE HOT MELT ADHESIVES ARIZONA CHEMICAL COMPANY (US) 1999-06-08 US disclosed
US-5807915-A HEAT RESISTANCE ARIZONA CHEMICAL COMPANY (US) 1998-09-15 US disclosed
EP-0852604-A4 1998-08-26 EP disclosed
US-5789474-A HOT MELT ADHESIVE ARIZONA CHEMICAL COMPANY (US) 1998-08-04 US disclosed
EP-0852604-A1 A POLYPHENYLENE OXIDE DELIVERY SYSTEM FOR ADHESIVE COMPOSITIONS ARIZONA CHEMICAL COMPANY (US) 1998-07-15 EP disclosed
EP-0381056-B1 Method for preparing an impact resistant thermoplastic resin composition MITSUBISHI CHEM CORP (JP) 1997-09-03 EP disclosed
WO-1997011997-A1 A POLYPHENYLENE OXIDE DELIVERY SYSTEM FOR ADHESIVE COMPOSITIONS ARIZONA CHEMICAL COMPANY (US) 1997-04-03 WO disclosed
EP-0520146-B1 Process for preparing a thermoplastic resin composition MITSUBISHI CHEM CORP (JP) 1997-01-15 EP disclosed
US-5091473-A Polyamide, polyphenylene ether, block polymer, unsaturated acid or anhydride dispension, hydrogenated impact strength, rigidity, heat resistance MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1992-02-25 US disclosed
EP-0454156-A2 Thermoplastic resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 1991-10-30 EP disclosed
US-5026787-A Blends of polyphenylene ether, polyamides, unsaturated compounds MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-06-25 US disclosed
US-5001181-A polyamide blends with dispersed particles of polyphenylene ether which contain dispersed filler particles; strength, flexibility, solvent resistance MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) 1991-03-19 US disclosed
EP-0415344-A1 Resin composition and process for preparing it MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-03-06 EP disclosed
EP-0381056-A2 Impact resistant thermoplastic resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 1990-08-08 EP disclosed
EP-0067217-A4 COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER. GEN ELECTRIC (US) 1983-05-16 EP disclosed
EP-0067217-A1 COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER GENERAL ELECTRIC COMPANY (US) 1982-12-22 EP disclosed
US-4365042-A Compositions of polyphenylene oxides with EPDM-silicone rubber GENERAL ELECTRIC COMPANY (US) 1982-12-21 US disclosed
WO-1982002204-A1 COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER GEN ELECTRIC (US) 1982-07-08 WO disclosed