Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 2/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.37 |
| ▸ | PAM | P19021 | 3/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829993 | 0.88 | MGAM (0.48) | MGAMGAASIMGAM2GPR174 | |
| SCHEMBL9204032 | 0.84 | MGAM (0.50) | MGAMGAASIMGAM2GPR174 | |
| SCHEMBL27860204 | 0.81 | MGAM (0.40) | MGAMGAASIMGAM2PAM | |
| SCHEMBL5285283 | 0.80 | EGLN1 (0.43) | PAMTSHRALDH1A1 | |
| SCHEMBL4848958 | 0.80 | GAA (0.65) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL13370395 | 0.78 | EPHX1 (0.45) | MGAMGAASIMGAM2LDHA | |
| SCHEMBL11355140 | 0.78 | ALDH1A1 (0.34) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL11355143 | 0.78 | ALOX15 (0.38) | LDHASRRGPR174TSHRALDH1A1 | |
| SCHEMBL4638003 | 0.78 | PAM (0.46) | MGAMGAASIMGAM2PAM | |
| SCHEMBL16068775 | 0.77 | HSD17B10 (0.39) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076425-A1 | IMPROVED SYNTHESIS OF MACROCYCLIC TETRAAMIDO COMPOUNDS AND NEW METAL INSERTION PROCESS | CARNEGIE MELLON UNIVERSITY (US) | 2004-09-10 | — | — | WO | disclosed |
| US-5296501-A | Bactericides | ROUSSEL UCLAF (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5030715-A | Antibacterial agents; immunomodulators; auto immune diseases | ROUSSEL UCLAF (FR) | 1991-07-09 | — | — | US | disclosed |