Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830990 | 0.81 | MEN1 (0.40) | L3MBTL1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6830833 | 0.79 | KDM4E (0.48) | NPC1RAB9AALDH1A1MAPTMAPK1 | |
| SCHEMBL6829509 | 0.78 | L3MBTL1 (0.40) | L3MBTL1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6829403 | 0.73 | SCN10A (0.63) | L3MBTL1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6644346 | 0.72 | PIK3CA (0.39) | L3MBTL1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6643919 | 0.72 | RAB9A (0.46) | L3MBTL1NPC1RAB9AMAPTLMNA | |
| SCHEMBL6645905 | 0.71 | RAB9A (0.44) | NPC1RAB9AALDH1A1MAPTMAPK1 | |
| SCHEMBL6825969 | 0.70 | SCN10A (0.52) | NPC1RAB9AALDH1A1MAPTGAA | |
| SCHEMBL6828987 | 0.70 | SCN10A (0.52) | L3MBTL1ALDH1A1TSHRHPGDSCN10A | |
| SCHEMBL27960592 | 0.69 | HPGD (0.74) | L3MBTL1NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |