Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500200 | 0.92 | CES2 (0.38) | SMN1; SMN2CES2CES1ACHENFE2L2 | |
| SCHEMBL13136869 | 0.86 | — | — | |
| SCHEMBL5892514 | 0.84 | HTR7 (0.39) | CES2CES1SLC6A3 | |
| SCHEMBL3458032 | 0.81 | CYP2C9 (0.41) | SMN1; SMN2ACHECYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6829603 | 0.79 | CES2 (0.31) | CES2CES1 | |
| SCHEMBL5892480 | 0.78 | ACHE (0.36) | CES2CES1ACHENFE2L2PARP1 | |
| SCHEMBL7858647 | 0.77 | CES2 (0.41) | CES2CES1ACHENFE2L2PARP1 | |
| SCHEMBL7738382 | 0.77 | CYP3A4 (0.41) | ALDH1A1MAOB | |
| SCHEMBL6829118 | 0.77 | ALDH1A1 (0.36) | CYP1A2ALDH1A1CHRNB4CHRNA3SLC6A3 | |
| SCHEMBL14983435 | 0.77 | ACHE (0.41) | ACHEHPGDALDH1A1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037816-A1 | BENZOFURAN COMPOUNDS HAVING ANTITUMOR ACTIVITY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-05-06 | — | — | WO | disclosed |