Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829032 | 0.83 | KMT2A (0.40) | RAB9ATHRBNAMPTLMNAKMT2A | |
| SCHEMBL6923840 | 0.83 | MGLL (0.59) | RAB9ATHRBKMT2ASMN1; SMN2GAA | |
| SCHEMBL13724309 | 0.74 | KMT2A (0.52) | THRBKMT2ASMN1; SMN2GAAKDM4E | |
| SCHEMBL25238984 | 0.73 | MGLL (0.60) | THRBSMN1; SMN2GAAKDM4EGLA | |
| SCHEMBL6647923 | 0.72 | NLRP3 (0.48) | THRBNAMPTLMNAKMT2A | |
| SCHEMBL3861581 | 0.72 | LTA4H (0.45) | RAB9ATHRBLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL18474099 | 0.72 | MGLL (0.67) | MGLL | |
| SCHEMBL28230841 | 0.71 | TDP1 (0.43) | THRBNAMPTLMNAKMT2AGAA | |
| SCHEMBL6679215 | 0.70 | SMN1; SMN2 (0.54) | RAB9ALMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL6920000 | 0.70 | MGLL (0.41) | RAB9ATHRBNAMPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |