Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | PKLR | P30613 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920999 | 0.95 | PKLR (0.48) | ALDH1A1PKLRRXFP1POLBLMNA | |
| SCHEMBL6922336 | 0.83 | ALDH1A1 (0.56) | ALDH1A1POLBLMNAPARP1HSD17B10 | |
| SCHEMBL6927936 | 0.81 | ALDH1A1 (0.56) | ALDH1A1RXFP1POLBLMNAL3MBTL1 | |
| SCHEMBL6930350 | 0.81 | ALDH1A1 (0.54) | ALDH1A1RXFP1POLBLMNAL3MBTL1 | |
| SCHEMBL6828029 | 0.81 | ALDH1A1 (0.54) | ALDH1A1POLBLMNAHSD17B10 | |
| SCHEMBL6827973 | 0.79 | PKM (0.61) | ALDH1A1POLBLMNAL3MBTL1TP53 | |
| SCHEMBL6923759 | 0.79 | POLB (0.57) | ALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL6828049 | 0.79 | ALDH1A1 (0.62) | ALDH1A1POLBLMNATP53 | |
| SCHEMBL6923737 | 0.79 | POLB (0.52) | ALDH1A1RXFP1POLBLMNAL3MBTL1 | |
| SCHEMBL6831335 | 0.79 | ALDH1A1 (0.67) | ALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | disclosed |