SCHEMBL683180

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL873386	0.80	PDE4A (0.46)	KDM4ETDP1CA2TSHRGLA
	SCHEMBL131870	0.78	ALDH1A1 (0.46)	KDM4ETDP1CA2SMN1; SMN2LMNA
	SCHEMBL29419589	0.77	CA2 (0.56)	KDM4ETDP1CA2TSHRGLA
	SCHEMBL20509	0.77	CA2 (0.56)	KDM4ETDP1CA2TSHRGLA
	SCHEMBL4291308	0.76	ALDH1A1 (0.46)	KDM4ETDP1CA2SMN1; SMN2LMNA
	SCHEMBL1256865	0.75	CA2 (0.54)	KDM4ETDP1CA2TSHRGLA
	SCHEMBL31096045	0.74	PDE10A (0.48)	KDM4ETDP1CA2SMN1; SMN2MAPT
	SCHEMBL21823383	0.74	PDE10A (0.48)	KDM4ETDP1CA2SMN1; SMN2MAPT
	Methyl Alcohol SCHEMBL28799088	0.73	CA2 (0.52)	KDM4ETDP1CA2TSHRSMN1; SMN2
	Ethyne SCHEMBL28045684	0.73	CA2 (0.52)	KDM4ETDP1CA2TSHRGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.