Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 13/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831906 | 1.00 | MTNR1A (0.47) | MTNR1AMCHR1ADRA2AADRA1AHRH1 | |
| SCHEMBL6456622 | 0.86 | SIGMAR1 (0.48) | MCHR1ADRA2ACDK2GSK3BCDK5 | |
| SCHEMBL6456613 | 0.86 | SIGMAR1 (0.48) | MCHR1ADRA2ACDK2GSK3BCDK5 | |
| SCHEMBL6875277 | 0.82 | EPHX1 (0.56) | MCHR1 | |
| SCHEMBL6875271 | 0.82 | EPHX1 (0.56) | MCHR1 | |
| SCHEMBL4032879 | 0.82 | MCHR1 (0.61) | MTNR1AMCHR1ADRA2AADRA1AHRH1 | |
| SCHEMBL4036493 | 0.82 | MCHR1 (0.61) | MTNR1AMCHR1ADRA2AADRA1AHRH1 | |
| SCHEMBL6877485 | 0.82 | MCHR1 (0.52) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6877476 | 0.82 | MCHR1 (0.52) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6867769 | 0.81 | MEN1 (0.41) | MCHR1ADRA2AFLT3TYRO3MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |