Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832568 | 0.93 | ENPP1 (0.44) | ENPP1KMT2ATHRBTDP1GAA | |
| SCHEMBL6834536 | 0.88 | STS (0.39) | KMT2ATDP1GAASTSCA12 | |
| SCHEMBL6832979 | 0.80 | STS (0.40) | STS | |
| SCHEMBL7069550 | 0.80 | CA12 (0.40) | KMT2ATDP1GAASTSALDH1A1 | |
| SCHEMBL6829303 | 0.80 | PPARA (0.40) | KMT2A | |
| SCHEMBL6829239 | 0.78 | STS (0.38) | KMT2ASTSMEN1 | |
| SCHEMBL7115003 | 0.75 | CA12 (0.38) | KMT2ATDP1GAASTSALDH1A1 | |
| SCHEMBL6832494 | 0.74 | CA12 (0.41) | KMT2ATDP1STSALDH1A1CA12 | |
| SCHEMBL6832055 | 0.72 | MTNR1A (0.44) | — | |
| SCHEMBL6829427 | 0.71 | MTNR1A (0.43) | KMT2ACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453795-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS | Dr. Reddy's Laboratories Ltd. (IN) | 2004-09-08 | — | — | EP | claimed |
| WO-2003048116-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS ____________ | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-06-12 | — | — | WO | claimed |
| EP-1453795-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS | Dr. Reddy's Laboratories Ltd. (IN) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048116-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS ____________ | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-06-12 | — | — | WO | disclosed |