Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829303 | 0.92 | PPARA (0.40) | MTNR1AMTNR1B | |
| SCHEMBL6832979 | 0.91 | STS (0.40) | — | |
| SCHEMBL6829427 | 0.84 | MTNR1A (0.43) | MTNR1AMTNR1B | |
| SCHEMBL6834536 | 0.83 | STS (0.39) | — | |
| Water SCHEMBL5161066 | 0.81 | HTR1A (0.38) | MTNR1AMTNR1B | |
| SCHEMBL6829239 | 0.81 | STS (0.38) | — | |
| SCHEMBL6832486 | 0.78 | TOP2A (0.39) | HDAC1 | |
| SCHEMBL7069550 | 0.74 | CA12 (0.40) | — | |
| SCHEMBL6832977 | 0.72 | ENPP1 (0.44) | — | |
| SCHEMBL10179751 | 0.71 | PPARA (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453795-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS | Dr. Reddy's Laboratories Ltd. (IN) | 2004-09-08 | — | — | EP | claimed |
| WO-2003048116-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS ____________ | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-06-12 | — | — | WO | claimed |
| EP-1453795-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS | Dr. Reddy's Laboratories Ltd. (IN) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048116-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS ____________ | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-06-12 | — | — | WO | disclosed |