SCHEMBL6833073

SCHEMBL6833073

N#Cc1ccc(NC(=O)c2noc3cc(OS(=O)(=O)c4ccccc4)ccc23)c(C(=O)O)c1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALPL P05186 4/20 0.44
ALB P02768 1/20 0.42
MAOB P27338 2/20 0.40
P2RY2 P41231 1/20 0.38
GPR17 Q13304 1/20 0.38
ALPI P09923 3/20 0.38
HIF1A Q16665 7/20 0.37
PYGL P06737 1/20 0.37
PYGM P11217 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6835761 0.87 ALB (0.39) ALBMAOBHIF1APYGLPYGM
SCHEMBL6818920 0.86 ALB (0.42) ALPLALBMAOBP2RY2GPR17
SCHEMBL6832994 0.85 HIF1A (0.46) ALBHIF1A
SCHEMBL6830330 0.84 SLC16A3 (0.44) MAOB
SCHEMBL6710401 0.84 ALPL (0.39) ALPLMAOBP2RY2GPR17ALPI
SCHEMBL6713524 0.84 ALPL (0.41) ALPLMAOBP2RY2GPR17ALPI
SCHEMBL6834401 0.83 GPR27 (0.46) ALBHIF1A
SCHEMBL6833638 0.83 KDM4E (0.41) ALBHIF1APYGLPYGM
SCHEMBL6830490 0.82 HIF1A (0.55) ALBHIF1A
SCHEMBL6818222 0.82 ALB (0.48) ALBMAOBHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 ALPL 2286/4885ALB 1417/4885MAOB 1623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.