Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ITK | Q08881 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.45 |
| ▸ | RELA | Q04206 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2306421 | 0.87 | DGAT1 (0.82) | DGAT1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1747992 | 0.87 | DGAT1 (0.82) | DGAT1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2306998 | 0.87 | DGAT1 (0.82) | DGAT1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2393849 | 0.84 | DGAT1 (0.77) | DGAT1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2308612 | 0.84 | DGAT1 (0.77) | DGAT1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2306561 | 0.79 | DGAT1 (0.69) | DGAT1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2312049 | 0.79 | DGAT1 (0.69) | DGAT1NPC1RAB9AKMT2AMEN1 | |
| Bicarbonate SCHEMBL2308618 | 0.79 | DGAT1 (0.67) | DGAT1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2307191 | 0.79 | DGAT1 (0.82) | DGAT1NPC1RAB9APOLBSCD | |
| SCHEMBL2396211 | 0.79 | DGAT1 (0.82) | DGAT1NPC1RAB9APOLBSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040224997-A1 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | BAYER PHARMACEUTICALS CORPORATION | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224997-A1 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | FABP4, GPR119, LIPC | DGAT1 34/4885NPC1 187/4885RAB9A 2066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.