Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 10/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.46 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.45 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819558 | 0.87 | POLB (0.51) | PLK1AKR1C2AKR1C1POLBSTING1 | |
| SCHEMBL6833223 | 0.86 | POLB (0.52) | PLK1AKR1C2AKR1C1POLBSTING1 | |
| SCHEMBL6818461 | 0.85 | PLK1 (0.56) | PLK1AKR1C2AKR1C1PLK3MCL1 | |
| SCHEMBL6834239 | 0.84 | POLB (0.52) | PLK1AKR1C2AKR1C1POLBSTING1 | |
| SCHEMBL6830480 | 0.84 | POLB (0.52) | PLK1AKR1C2AKR1C1POLBSTING1 | |
| SCHEMBL6830598 | 0.83 | POLB (0.53) | PLK1AKR1C2AKR1C1POLBSTING1 | |
| SCHEMBL6833147 | 0.83 | POLB (0.53) | PLK1AKR1C2AKR1C1POLBSTING1 | |
| SCHEMBL6813815 | 0.81 | PLK1 (0.57) | PLK1AKR1C2AKR1C1POLBKCNK2 | |
| SCHEMBL6835741 | 0.80 | NFKB1 (0.57) | PLK1AKR1C2AKR1C1POLBSTING1 | |
| SCHEMBL11270225 | 0.78 | TSHR (0.54) | PLK1KDM4ETDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | PLK1 4270/4885AKR1C2 2596/4885AKR1C1 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.