SCHEMBL6833166

SCHEMBL6833166

CS(=O)(=O)c1ccc(-c2ccc3onc(C(=O)Nc4ccc(C#N)cc4C(=O)O)c3c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALB P02768 2/20 0.45
HIF1A Q16665 4/20 0.38
PRSS12 P56730 2/20 0.38
KIT P10721 1/20 0.36
PTGS2 P35354 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
KAT6A Q92794 1/20 0.35
SIRT2 Q8IXJ6 1/20 0.35
PTPN1 P18031 1/20 0.34
ACLY P53396 1/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6834186 0.89 HIF1A (0.49) ALBHIF1APRSS12KAT6APTPN1
SCHEMBL6835695 0.86 ALB (0.46) ALBHIF1ASIRT2
SCHEMBL6817726 0.86 HIF1A (0.41) ALBHIF1APRSS12
SCHEMBL6819451 0.86 ALB (0.45) ALBPRSS12KITKAT6ASIRT2
SCHEMBL6830338 0.85 ALB (0.47) ALBHIF1AKAT6A
SCHEMBL6830645 0.85 ALB (0.48) ALBHIF1APRSS12
SCHEMBL7158818 0.85 ALB (0.46) ALBHIF1A
SCHEMBL6818893 0.84 ALDH1A1 (0.49) ALB
SCHEMBL6834064 0.84 ALB (0.42) ALBHIF1A
SCHEMBL6833090 0.83 ALB (0.43) ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 ALB 1417/4885HIF1A 220/4885PRSS12 4112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.