SCHEMBL6830645

SCHEMBL6830645

N#Cc1ccc(NC(=O)c2noc3ccc(S(=O)(=O)Cl)cc23)c(C(=O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALB P02768 2/20 0.48
HIF1A Q16665 7/20 0.38
CDK2 P24941 1/20 0.36
CCR2 P41597 1/20 0.35
GPR27 Q9NS67 2/20 0.35
AVPR2 P30518 1/20 0.35
FLT1 P17948 1/20 0.34
FLT4 P35916 1/20 0.34
KDR P35968 1/20 0.34
PRSS12 P56730 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA12 O43570 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
MAP2K1 Q02750 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6830338 0.89 ALB (0.47) ALBHIF1ACDK2CCR2GPR27
SCHEMBL7158818 0.88 ALB (0.46) ALBHIF1ACDK2CCR2MAOA
SCHEMBL6835695 0.88 ALB (0.46) ALBHIF1A
SCHEMBL6830643 0.87 ALB (0.36) ALBHIF1AFLT1FLT4KDR
SCHEMBL6833969 0.86 GPR27 (0.48) ALBHIF1ACCR2GPR27AVPR2
SCHEMBL6833171 0.86 HIF1A (0.37) ALBHIF1AGPR27AVPR2
SCHEMBL6818893 0.86 ALDH1A1 (0.49) ALB
SCHEMBL6834683 0.86 ALB (0.59) ALB
SCHEMBL6833166 0.85 ALB (0.45) ALBHIF1APRSS12
SCHEMBL7073443 0.85 ALB (0.43) ALBHIF1ACDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 ALB 1417/4885HIF1A 220/4885CDK2 4509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.