Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.41 |
| ▸ | MMP3 | P08254 | 6/20 | 0.41 |
| ▸ | MMP9 | P14780 | 5/20 | 0.39 |
| ▸ | MMP14 | P50281 | 5/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833383 | 1.00 | MMP2 (0.41) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6137308 | 0.99 | MMP2 (0.42) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6137306 | 0.99 | MMP2 (0.42) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6833385 | 0.90 | MMP2 (0.38) | MMP2MMP3MMP9MMP14MMP1 | |
| Cyclohexylamine SCHEMBL6137474 | 0.89 | PPARG (0.37) | MMP2MMP3MMP9MMP14MMP1 | |
| Cyclohexylamine SCHEMBL6137479 | 0.89 | PPARG (0.37) | MMP2MMP3MMP9MMP14MMP1 | |
| Amantadine SCHEMBL6931289 | 0.88 | MMP2 (0.35) | MMP2MMP3MMP9MMP14MMP1 | |
| Amantadine SCHEMBL6931282 | 0.88 | MMP2 (0.35) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6137476 | 0.82 | CDK2 (0.36) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL5404174 | 0.82 | GRIK1 (0.51) | GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6750363-B2 | Olefination process to itaconate and succinate derivatives | PFIZER, INC. | 2004-06-15 | — | — | US | disclosed |
| US-20020188121-A1 | Novel olefination process to itaconate and succinate derivatives | DERRICK ANDREW MICHAEL (GB) | 2002-12-12 | — | — | US | disclosed |
| US-20020058832-A1 | Novel olefination process to itaconate and succinate derivatives | PFIZER INC. | 2002-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020188121-A1 | Novel olefination process to itaconate and succinate derivatives | HOGA1, OGDH, HADHA | MMP2 3089/4885MMP3 3048/4885MMP9 3859/4885 |
| US-20020058832-A1 | Novel olefination process to itaconate and succinate derivatives | HOGA1, HADHA, OGDH | MMP2 2827/4885MMP3 3007/4885MMP9 3662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.