Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 3/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776640 | 0.92 | KDM1A (0.42) | KDM1ARCOR1EHMT2NQO2KAT2B | |
| SCHEMBL2777536 | 0.84 | KCNH2 (0.40) | KDM1ARCOR1POLBRAD52HSD17B10 | |
| SCHEMBL6933547 | 0.81 | KDM1A (0.44) | KDM1ARCOR1EHMT2WHR1 | |
| SCHEMBL6678946 | 0.81 | NCF1 (0.44) | KDM1ARCOR1EHMT2TERTPOLB | |
| SCHEMBL6679538 | 0.80 | KDM1A (0.43) | KDM1ARCOR1EHMT2WHR1 | |
| SCHEMBL2776163 | 0.80 | POLB (0.41) | POLBMAPTRAD52SCN9A | |
| SCHEMBL2774175 | 0.80 | RAD52 (0.36) | KDM1ARCOR1EHMT2RAD52MKNK1 | |
| SCHEMBL6676209 | 0.79 | KMT5A (0.44) | CRHBPCRHR2KEAP1NFE2L2KDM1A | |
| SCHEMBL6673922 | 0.79 | DNM2 (0.37) | KDM1ARCOR1EHMT2RAD52WHR1 | |
| SCHEMBL2774178 | 0.78 | KCNH2 (0.40) | KDM1ARCOR1EHMT2POLBRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040192686-A1 | Benzoazine mono-N-oxides and benzoazine 1,4 dioxides and compositions therefrom for the therapeutic use in cancer treatments | AUCKLAND UNISERVICES LIMITED (NZ) | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192686-A1 | Benzoazine mono-N-oxides and benzoazine 1,4 dioxides and compositions therefrom for the therapeutic use in cancer treatments | NPM1, DUOX1, NOX5 | CRHBP 4700/4885CRHR2 3115/4885KEAP1 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.