SCHEMBL6833763

SCHEMBL6833763

Cn1c(C(=O)Nc2ccc(C#N)cc2C(=O)O)cc2cccc(NC(=O)CF)c21

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALB P02768 3/20 0.39
PKM P14618 1/20 0.38
LMNA P02545 3/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
NOTUM Q6P988 1/20 0.36
MAPK14 Q16539 1/20 0.36
KMT2A Q03164 2/20 0.36
TRPM4 Q8TD43 1/20 0.36
HTT P42858 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
GFER P55789 1/20 0.35
MEN1 O00255 1/20 0.35
MAP2K1 Q02750 1/20 0.35
CDK2 P24941 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6830873 0.88 LMNA (0.38) ALBPKMLMNAKMT2AMEN1
SCHEMBL6833427 0.87 ALB (0.50) ALBLMNATP53MAPTKMT2A
SCHEMBL6834048 0.86 ALB (0.42) ALBPKMLMNATP53MAPT
SCHEMBL6833985 0.84 ALB (0.42) ALBLMNATP53MAPTNOTUM
SCHEMBL6834424 0.84 ALB (0.43) ALBPKMLMNATP53MAPT
SCHEMBL6835608 0.84 ALB (0.40) ALBPKMLMNATP53MAPT
SCHEMBL6835709 0.84 ALB (0.40) ALBLMNATP53MAPTMAPK14
SCHEMBL6835787 0.84 CFD (0.47) ALBLMNAKMT2AHTTGFER
SCHEMBL6830635 0.84 ALB (0.41) ALBPKMLMNATP53MAPT
SCHEMBL6834135 0.83 ALB (0.39) ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US claimed
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 ALB 1417/4885PKM 3785/4885LMNA 3376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.