SCHEMBL6833845

SCHEMBL6833845

c1c[nH]c(-c2nc3c(C4CC4)nc4ccccc4c3n2CCC2CCNCC2)c1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 5/20 0.38
MAOB P27338 1/20 0.37
HTR6 P50406 1/20 0.37
NPY1R P25929 3/20 0.36
HTR4 Q13639 1/20 0.36
SLC6A4 P31645 3/20 0.33
MERTK Q12866 1/20 0.32
TLR7 Q9NYK1 1/20 0.31
AVPR2 P30518 1/20 0.31
AVPR1A P37288 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6924876 0.89 HTR4 (0.39) ACP1NPY1RHTR4SLC6A4MERTK
SCHEMBL6927725 0.88 NPY1R (0.41) ACP1MAOBHTR6NPY1RHTR4
SCHEMBL6838557 0.87 MAOB (0.39) ACP1MAOBHTR6NPY1RHTR4
SCHEMBL6838088 0.87 MERTK (0.39) ACP1NPY1RHTR4SLC6A4MERTK
SCHEMBL6838715 0.86 ACP1 (0.37) ACP1NPY1RHTR4SLC6A4MERTK
SCHEMBL6837643 0.77 ACP1 (0.38) ACP1TLR7
SCHEMBL6840070 0.77 ACP1 (0.49) ACP1NPY1R
SCHEMBL6838596 0.76 CCR3 (0.34) ACP1NPY1RSLC6A4
SCHEMBL6838504 0.76 KHK (0.33) ACP1HTR6NPY1R
SCHEMBL7500056 0.76 NPY1R (0.38) ACP1NPY1RSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040054182-A1 1h-imidazopyridine derivatives HOKURIKU SEIYAKU CO., LTD. (JP) 2004-03-18 US disclosed
EP-1256582-A1 1H-IMIDAZOPYRIDINE DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2002-11-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040054182-A1 1h-imidazopyridine derivatives IL2, IL1A, IL4 ACP1 490/4885MAOB 3539/4885HTR6 3067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.