SCHEMBL6834112

SCHEMBL6834112

N#Cc1ccc(NC(=O)c2cc3cccc(OCc4ccccc4)c3[nH]2)c(C(=O)O)c1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPIA P62937 1/20 0.44
RXFP1 Q9HBX9 1/20 0.43
SGMS2 Q8NHU3 1/20 0.42
MRGPRX4 Q96LA9 2/20 0.42
TP53 P04637 2/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
TRPM4 Q8TD43 1/20 0.41
MET P08581 1/20 0.41
LRRK2 Q5S007 1/20 0.41
SRD5A2 P31213 1/20 0.41
CYP19A1 P11511 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6833977 0.84 TRPM4 (0.41) POLBTRPM4
SCHEMBL6710091 0.83 PPIA (0.40) PPIARXFP1SGMS2TP53LMNA
SCHEMBL6834504 0.83 LMNA (0.47) RXFP1LMNA
SCHEMBL6710247 0.83 PPIA (0.40) PPIARXFP1SGMS2TP53LMNA
SCHEMBL6834154 0.82 KMT2A (0.49) RXFP1MAPT
SCHEMBL6834215 0.82 RXFP1 (0.53) RXFP1TP53LMNAPOLBMAPT
SCHEMBL6833156 0.82 ALB (0.43)
SCHEMBL6833881 0.82 MEN1 (0.48) LMNAPOLBMAPTTRPM4
SCHEMBL6834023 0.82 HCAR2 (0.43)
SCHEMBL6835826 0.81 KDM4E (0.61) MAPTSRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US claimed
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed
WO-2004018428-A1 ANTIBACTERIAL BENZOIC ACID DERIVATIVES PHARMACIA & UPJOHN COMPANY LLC (US) 2004-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 PPIA 4193/4885RXFP1 3523/4885SGMS2 4791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.