Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77335 | 0.87 | POLB (0.46) | ALDH1A1MAPTLMNATSHRTDP1 | |
| SCHEMBL4365843 | 0.85 | POLB (0.48) | ALDH1A1MAPTLMNATSHRTDP1 | |
| SCHEMBL6036699 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNATSHRTDP1 | |
| SCHEMBL2337048 | 0.84 | POLB (0.47) | ALDH1A1MAPTLMNATSHRTDP1 | |
| SCHEMBL9512370 | 0.79 | TDP1 (0.48) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL18509214 | 0.78 | GRIN2D (0.39) | ALDH1A1MAPTLMNATSHRTDP1 | |
| SCHEMBL8214283 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNATDP1CYP3A4 | |
| SCHEMBL7444129 | 0.77 | LMNA (0.47) | ALDH1A1MAPTLMNATSHRTDP1 | |
| SCHEMBL1538857 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNATSHRTDP1 | |
| SCHEMBL27824900 | 0.77 | MAPT (0.42) | ALDH1A1MAPTLMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106983751-A | Two ring substituted uracils and application thereof | 拜耳医药股份有限公司 | 2017-07-28 | — | — | CN | disclosed |
| US-6750335-B2 | NUCLEOSIDE FOR USE IN THE GENERATION OF PREFERENTIAL OLIGONUCEOTIDES | NIGU CHEMIE GMBH (DE) | 2004-06-15 | — | — | US | disclosed |
| EP-1224198-B1 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTING GROUPS | NIGU CHEMIE GMBH (DE) | 2003-04-23 | — | — | EP | disclosed |
| US-20020146737-A1 | Nucleoside derivatives with photolabile protective groups | NIGU CHEMIE GMBH (DE) | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020146737-A1 | Nucleoside derivatives with photolabile protective groups | XRN2, XPA, NSUN2 | ALDH1A1 1966/4885MAPT 4771/4885LMNA 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.