Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818219 | 0.90 | AKR1C2 (0.35) | LMNACYP1A2AKR1C2AKR1C1PKM | |
| Sulfuric Acid SCHEMBL6819163 | 0.86 | AKR1C2 (0.44) | LMNACYP1A2HIF1AAKR1C2AKR1C1 | |
| SCHEMBL6713674 | 0.81 | LMNA (0.37) | LMNACYP1A2HIF1AAKR1C2AKR1C1 | |
| SCHEMBL6710016 | 0.81 | LMNA (0.36) | LMNACYP1A2HIF1AAKR1C2AKR1C1 | |
| SCHEMBL6833135 | 0.79 | KCNK2 (0.40) | LMNACYP1A2HIF1AAKR1C2AKR1C1 | |
| Sulfuric Acid SCHEMBL6834053 | 0.77 | KCNK2 (0.38) | LMNACYP1A2HIF1AAKR1C2AKR1C1 | |
| SCHEMBL6833681 | 0.76 | SMN1; SMN2 (0.44) | LMNACYP1A2AKR1C2PKMKMT2A | |
| Nitric Acid SCHEMBL6833828 | 0.74 | SMN1; SMN2 (0.43) | LMNACYP1A2AKR1C2PKMKMT2A | |
| SCHEMBL6710398 | 0.74 | LMNA (0.37) | LMNACYP1A2HIF1APKMRORC | |
| SCHEMBL7129851 | 0.73 | LMNA (0.36) | LMNACYP1A2HIF1APKMRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | LMNA 3376/4885CYP1A2 710/4885HIF1A 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.