Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.62 |
| ▸ | PPARG | P37231 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508302 | 0.89 | SMN1; SMN2 (0.72) | TP53MAPTMEN1HTTKMT2A | |
| SCHEMBL8366932 | 0.84 | RAB9A (0.76) | TP53MAPTMEN1HTTKMT2A | |
| SCHEMBL6834686 | 0.83 | AGTR1 (0.52) | TP53MAPTMEN1HTTKMT2A | |
| SCHEMBL16556586 | 0.81 | MEN1 (0.63) | TP53MAPTMEN1HTTKMT2A | |
| SCHEMBL9740603 | 0.80 | ALDH1A1 (0.66) | MEN1KMT2ALMNAAGTR1AGTR2 | |
| SCHEMBL9598289 | 0.79 | PKM (0.68) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL6833621 | 0.79 | TNF (0.81) | TP53MAPTMEN1HTTKMT2A | |
| SCHEMBL16556627 | 0.79 | MEN1 (0.60) | TP53MAPTMEN1HTTKMT2A | |
| SCHEMBL229324 | 0.79 | MEN1 (0.78) | TP53MAPTMEN1HTTKMT2A | |
| SCHEMBL13144806 | 0.78 | CYP1A2 (0.80) | MAPTMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6749977-B1 | PROVIDE GOOD DYE-FORMING ACTIVITY AND WHICH, AT THE SAME TIME, YIELD LITTLE OR NO INCREASED FOG AND/ OR PROVIDE LITTLE OR NO DECREASE IN DMAX AFTER STORAGE | EASTMAN KODAK COMPANY | 2004-06-15 | — | — | US | disclosed |