Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834770 | 0.82 | CHRNA7 (0.49) | MAPTKMT2AMEN1CHRNA7POLB | |
| SCHEMBL5607983 | 0.76 | CHRNA7 (0.60) | GAAHTTMAPTL3MBTL1KMT2A | |
| SCHEMBL5608032 | 0.75 | MAPT (0.48) | HTTMAPTKMT2AMEN1RAB9A | |
| SCHEMBL1540091 | 0.72 | ALDH1A1 (0.70) | GAAHTTMAPTL3MBTL1KMT2A | |
| SCHEMBL6833832 | 0.72 | TMPRSS4 (0.42) | HTTMAPTKMT2AMEN1POLB | |
| SCHEMBL3590371 | 0.71 | LCK (0.70) | HTTMAPTKMT2AMEN1CHRNA7 | |
| SCHEMBL5607284 | 0.71 | KMT2A (0.36) | MAPTL3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL3591878 | 0.70 | RAB9A (0.57) | GAAHTTMAPTL3MBTL1KMT2A | |
| SCHEMBL3597783 | 0.70 | KMT2A (0.61) | HTTMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL3591255 | 0.67 | ALDH1A1 (0.78) | GAAMAPTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054186-A1 | Cyclic protein tyrosine kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-03-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054186-A1 | Cyclic protein tyrosine kinase inhibitors | LCK, ABL1, BTK | GAA 2354/4885HTT 4034/4885MAPT 3114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.