SCHEMBL7528831

SCHEMBL7528831

CC(C(=O)Nc1ccc(C(=O)N2CCCC2)c(Br)c1)c1cc(C(=N)N)ccc1O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
F10 P00742 13/20 0.46
PRSS1 P07477 5/20 0.46
HSD11B1 P28845 1/20 0.39
PLAU P00749 5/20 0.39
F2 P00734 4/20 0.39
PLAT P00750 4/20 0.39
MBTD1 Q05BQ5 1/20 0.38
L3MBTL3 Q96JM7 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KMT2A Q03164 2/20 0.37
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
PLG P00747 2/20 0.37
TSHR P16473 1/20 0.37
F9 P00740 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7525529 0.99 F10 (0.45) F10PRSS1HSD11B1PLAUF2
SCHEMBL7525875 0.91 F10 (0.47) F10PRSS1HSD11B1PLAUF2
Hydrochloric Acid SCHEMBL7526160 0.90 F10 (0.46) F10PRSS1HSD11B1PLAUF2
SCHEMBL2995346 0.86 F10 (0.44) F10PRSS1HSD11B1PLAUF2
Hydrochloric Acid SCHEMBL7524480 0.86 F10 (0.43) F10PRSS1HSD11B1PLAUF2
SCHEMBL6555783 0.81 MBTD1 (0.41) F10PRSS1PLAUF2PLAT
Hydrochloric Acid SCHEMBL7558653 0.80 MBTD1 (0.41) F10PRSS1PLAUF2PLAT
SCHEMBL7156542 0.79 F10 (0.54) F10PRSS1HSD11B1PLAUF2
Hydrochloric Acid SCHEMBL7534381 0.79 F10 (0.53) F10PRSS1HSD11B1PLAUF2
SCHEMBL6554435 0.73 F10 (0.42) F10PRSS1PLAUF2PLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020151595-A1 Carboxylic acid amides having antithrombotic activity BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US claimed
US-20020151595-A1 Carboxylic acid amides having antithrombotic activity BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151595-A1 Carboxylic acid amides having antithrombotic activity SERPINC1, TFPI, F2 F10 30/4885PRSS1 879/4885HSD11B1 4056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.