Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224568 | 0.84 | GPR119 (0.42) | ALDH1A1KDM4EPOLB | |
| SCHEMBL5228930 | 0.77 | KDM4E (0.35) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL15353048 | 0.74 | DDB1 (0.40) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL20137787 | 0.69 | CYP46A1 (0.46) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL2930129 | 0.67 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL23647559 | 0.66 | CYP46A1 (0.44) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL8103240 | 0.64 | GRIN2B (0.41) | ALDH1A1KDM4ELMNAGAANPSR1 | |
| SCHEMBL30163900 | 0.64 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL9933469 | 0.64 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL9933442 | 0.64 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38524-E1 | Dipeptide derivatives as growth hormone secretagogues | PFIZER INC. | 2004-06-01 | — | — | US | disclosed |
| US-6251902-B1 | Dipeptide derivatives as growth hormone secretagogues | PFIZER INC. | 2001-06-26 | — | — | US | disclosed |